NUCLEIC ACID RELATED COMPOUNDS. 31. SMOOTH AND EFFICIENT PALLADIUM-COPPER CATALYZED COUPLING OF TERMINAL ALKYNES WITH 5-IODOURACIL NUCLEOSIDES

DOI: 10.1016/0040-4039(81)80115-3

Source and publish data:

Tetrahedron Letters p. 421 - 424 (1981)

Update date:2022-08-05

Topics:

Authors:

Robins, Morris J.

Barr, Philip J.

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Article abstract of DOI:10.1016/0040-4039(81)80115-3

Coupling of terminal alkynes with protected 5-iodouracil nucleosides in the presence of dichlorobis(triphenylphosphine)palladium and copper(I) iodide in triethylamine gives the corresponding 5-(alkyn-1-yl)uracil nucleosides in 72-92percent yields.

Full text of DOI:10.1016/0040-4039(81)80115-3

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