Structure-activity relationships of dermorphin analogues containing chiral piperazin-2-one and piperazine derivatives

DOI: 10.1248/cpb.44.856

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 856 - 859 (1996)

Update date:2022-08-05

Topics:

Authors:

Yamashita, Tetsushi

Hatamoto, Eiji

Takenaka, Hiroshi

Kojima, Yoshitane

Inoue, Yutaka

Gemba, Munekazu

Yasuda, Masahide

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Article abstract of DOI:10.1248/cpb.44.856

The amide and ester carbonyl groups of four piperazin-2-one derivatives (N,N′-ethylene-bridged dipeptide ethyl esters) constructed from (R)- or (S)-phenylalanine and glycine were reduced with borane-tetrahydrofuran complex to produce the corresponding pip

Full text of DOI:10.1248/cpb.44.856

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