Stereoselective synthesis of 1-bromo-(or 1-chloro-) 1,1-difluoro-2-alkenes

DOI: 10.1016/0022-1139(95)03340-8

Source and publish data:

Journal of Fluorine Chemistry p. 79 - 82 (1996)

Update date:2022-08-04

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Authors:

Tellier, Frederique

Sauvetre, Raymond

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Article abstract of DOI:10.1016/0022-1139(95)03340-8

A highly regio- and stereo-selective method for the introduction of a bromo- (or chloro-) difluoromethylene group into various unsaturated systems is described. The key step is the treatment of 1,1-difluoro-1-alken-3-ols with thionyl bromide (or chloride).

Full text of DOI:10.1016/0022-1139(95)03340-8

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