Archiv der Pharmazie p. 464 - 470 (1981)
Update date:2022-09-26
Topics:
Schoenen, Beate
Zymalkowski, Felix
Reaction of 3-bromoquinoline with ammonia gives 3-aminoquinoline (3) in good yield.Substitution of 3 is possible by treating the sodium salt of 3 with alkyl halides or by reductive alkylation with aromatic and aliphatic ketones.Amine exchange occurs by reaction of acetophenone Mannich bases with 3.Methyl vinyl ketone and acrylonitrile give no addition compounds with 3.Derivatives of trans-3-phenylglycidic acid react with 3 to give derivatives of β-phenylisoserine.
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Doi:10.1002/mrc.1270160111
(1981)Doi:10.1002/anie.202010958
(2021)Doi:10.1016/j.bmcl.2005.08.051
(2005)Doi:10.1016/S0040-4039(01)90251-5
(1981)Doi:10.1021/ic0492800
(2004)Doi:10.1021/jo00335a028
(1981)
