PHENOXAZINE DERIVATIVES - PRODUCTS OF THE REACTION OF o-AMINOPHENOL WITH CHALCONES

Article abstract of DOI:10.1007/BF00503476

The reaction of o-aminophenol with 4- and 4'-substituted chalcones and benzalacetones in methanol (with a tertiary amine as the catalyst), which leads to products of β addition of 2-aminophenoxazin-3-one to the C=C bond of an unsaturated ketone, was investigated.The activating role of the unsaturated ketone in the formation of a phenoxazine fragment was examined.The structures of the synthesized compounds were confirmed by IR, UV, PMR, and mass spectrometry.