Journal of Medicinal Chemistry p. 1531 - 1534 (1981)
Update date:2022-08-04
Topics: Synthesis NMR spectroscopy Mass spectrometry (MS) Antibacterial activity Minimum inhibitory concentration (MIC) HPLC (high-performance liquid chromatography) Enzyme inhibition Purification Structure-Activity Relationship (SAR) In vitro assay β-lactamase Carboxylic acid (-COOH)
Gottstein, William J.
Crast, Leonard B.
Graham, Robert G.
Haynes, Ute J.
McGregor, Donald M.
Potassium 2β-(chloromethyl)-2α-methylpenam-3α-carboxylate 1,1-dioxide (BL-P2013) and its pivaloyloxymethyl ester were prepared by the conversion of 6-aminopenicillanic acid to p-nitrobenzyl 6α-bromo-2,2-dimethylpenam-3α-carboxylate 1-oxide, which was rear
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Doi:10.1002/ejoc.201600479
(2016)Doi:10.1021/jm00343a011
(1982)Doi:10.1021/acs.joc.5b02241
(2015)Doi:10.1039/c39810000832
(1981)Doi:10.1021/jo01349a033
(1966)Doi:10.1007/BF00503661
(1982)