SIMPLE SYNTHESIS OF 9-(5-DEOXY-β-D-ERYTHRO-PENT-4-ENOFURANOSYL)ADENINE FROM ADENOSINE BY SELENOXIDE FRAGMENTATION

Article abstract of DOI:10.1246/cl.1981.1221

5'-Se-(2-Nitrophenyl)-5'-selenoadenosine (3) was selectively synthesized by the reaction of adenosine with 2-nitrophenylselenocyanate and tri-n-butylphosphine.The selenide 3 was oxidised by treatment with excess hydrogen peroxide to the corresponding sele