New Approach to Lythraceae Alkaloids: Total Synthesis of (+/-)-Vertaline

Article abstract of DOI:10.1021/jo00347a036

A new approach to Lythraceae alkaloids is described within the context of a total synthesis of (+/-)-vertaline (2).The use of N-silyl imines in the preparation of benzylic amines as well as a stereoselective bicycloannelation approach to the synthesis of quinolizidinones is discussed.