PHOTOINDUCED N-β-HYDROXYALKYLATION OF TROPAN DERIVATIVES

Article abstract of DOI:10.1007/BF01169671

The photooxidation of tropan derivatives by ketones was studied; the targeting of the reaction to the N-CH3 group with the formation of N-alkylation products and bis-tropan derivatives was demonstrated.The presence of two diastereomers in salts of N-alkyl derivatives of tropan was detected by PMR spectroscopy.An alternative method of synthesis of difficult-to-obtain amino alcohols was proposed.