An Efficient Synthesis of the Enantiomeric 17-Phosphasteroid System

DOI: 10.1021/jo00132a057

Source and publish data:

Journal of Organic Chemistry p. 2219 - 2220 (1982)

Update date:2022-08-05

Topics:

Authors:

Bodalski, Ryszard

Koszuk, Jacek

Krawczyk, Henryk

Pietrusiewicz, K. Michal

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00132a057

Enantiomeric trans-benzylphenyl<β-(carbomethoxy)vinyl>phosphine oxide (6) undergoes regio- and stereoselective cycloaddition to 1-vinylnaphthalene (5), providing two diastereomeric adducts 7a and 7b, which are further transformed into optically pure 17-phosphasteroid systems by intramolecular Dieckmann-type condensation.

Full text of DOI:10.1021/jo00132a057

Products guided by the article

Product name:(1R,2S)-2-((S)-Benzyl-phenyl-phosphinoyl)-1,2,3,4-tetrahydro-phenanthrene-1-carboxylic acid methyl ester

Cas No:81075-99-2

R&D Labs maybe for 81075-99-2

Hubei Xinghuo Chemical Co., Ltd.,

Contact:13925817279 13907299441

Address:Xinghuo Fine Chemistry Industrial Park, Xiaochang County, Hubei Province, China
ANHUI WEICHI CHEMICAL CO.,LTD

website:http://www.weichichem.com

Contact:+8613912949432

Address:Fine Chemical Industrial Base,Wujiang town,He County,Anhui China.
Tractus Company Limited

Contact:+852-8198 2399

Address:9E, Leapont Industrial Building, 18-28 Wo Liu Hang Road, Shatin, New Territories, Hong Kong
Xinji City Taida Sinopec Co., Ltd.

Contact:0086-311-85341278

Address:No.6, Nanhua Road,Xinji City Road,Hebei Province,China
Shandong Xinhua Pharmaceutical Co.,Ltd

website:http://www.xhzy.com

Contact:+86-533-2196801

Address:1 lutai road,zhangdian dis,Zibo City

Relevant to this article

BRANCHED CHAIN SUGARS. XXIX. SYNTHESIS OF MOENURONIC ACID (4-C-METHYL-D-GLUCURONIC ACID)

Doi:10.1246/bcsj.55.938
(1982)
Selective cyclooxygenase-2 inhibitors: Heteroaryl modified 1,2-diarylimidazoles are potent, orally active antiinflammatory agents

Doi:10.1021/jm0000719
(2000)
Synthesis of dl-3-Hydroxycuparene by a Claisen Rearrangement of Allyl Aryl Ether

Doi:10.1246/bcsj.55.208
(1982)
Cyclometallated Pd(II) azido complexes containing 6-phenyl-2,2′- bipyridyl or 2-phenylpyridyl derivatives: Synthesis and reactivity toward organic isocyanides and isothiocyanates

Doi:10.1039/b411432a
(2004)
Diastereoselective synthesis of all eight L-hexoses from L-ascorbic acid

Doi:10.1021/jo0521192
(2006)
Efficient synthesis of quaternary α-hydroxy acids by alkylation of α-ketoamide-derived dienediolates

Doi:10.1055/s-2005-918481
(2005)

Article Doi