
Chemistry of Heterocyclic Compounds p. 28 - 31 (1982)
Update date:2022-08-03
Topics:
Smirnov, V. A.
Zimichev, A. V.
Lyzhova, G. A.
Lipkin, A. E.
Depending on the substituent, the bromination of 4-(2-thienyl)thiazoles and 2-(2-thienyl)quinoline takes place in the 5 position of the thiophene or thiazole ring.When an amino group is present in the 2 position of the thiazole ring, bromination takes place in the 5 position of the thiazole ring.When excess brominating agent is present, a second bromine atom enters the 5 position of the free ring.
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(1982)