THE PROTECTION OF URACIL AND GUANINE RESIDUES IN OLIGONUCLEOTIDE SYNTHESIS

DOI: 10.1016/S0040-4039(01)83032-X

Source and publish data:

Tetrahedron Letters p. 4755 - 4758 (1981)

Update date:2022-08-04

Topics:

Authors:

Jones, Simon S.

Reese, Colin B.

Sibanda, Samson

Ubasawa, Aiko

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(01)83032-X

The protection of uracil and 2-N-acyl guanine residues with 4-O-phenyl and 6-O-(2-nitrophenyl) groups as in 7a (or 7b) and 9, respectively, is described.These O-aril protecting groups, which appear to withstand the usual conditions of oligonucleotide synthesis, may readily be removed by treatment with 2-nitrobenzaldoximate ions.

Full text of DOI:10.1016/S0040-4039(01)83032-X

Products guided by the article

Product name:2-(4-tert-Butyl-phenyl)-N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-hydroxymethyl-3-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-yl]-6-(2-nitro-phenoxy)-9H-purin-2-yl]-acetamide

Cas No:81793-93-3

R&D Labs maybe for 81793-93-3

Wuhan Chemwish Technology Co., Ltd

website:http://www.chemwish.com/

Contact:+86-27-67849912

Address:Room 1311, Unit 2, Block1, Innovation Road East Lake High-tech Development Zone Wuhan, Hubei，P.R. China
WENZHOU M&C FOREIGN TRADE CO.,LTD.

Contact:+86-577-88862917

Address:No.8 Liming West Road,Wenzhou,zhejiang,China
Ningbo Tide Imp. & Exp. Co., Ltd.

Contact:+86-571-8993 7933; +86-571-8993 6453

Address:7/F Anno Domini Building, Tower South, 8 Qiu Shi Road,Hangzhou,China.
Shanghai Rainbow Chemistry Co., Ltd.

Contact:+86-21-64968086-5815/5812

Address:3rd floor, Building 7, 251 Faladi Road, Zhangjiang Hi-Tech Park, Pudong District, Shanghai, P.R. China
Jinan Jiaquan Chemical Co.,Ltd

Contact:+86-531-62318366

Address:Room 502 of Yidonghuayuan No.601 Huaxin Road Licheng District Jinan China

Relevant to this article

Isolation of [1]ruthenocenophanes: Synthesis of polyruthenocenylstannanes by ring-opening polymerization

Doi:10.1002/anie.200454022
(2004)
Synthesis and evaluation of (17 alpha,20E)-21-[125I]iodo-19-norpregna-1,3,5(10),20-tetraene-3,17 -diol and (17 alpha,20E)-21-[125I]iodo-11 beta-methoxy-19-norpregna-1,3,5(10),20-tetraene-3,17-diol (17 alpha-(iodovinyl)estradiol derivatives) as high specific activity potential radiopharmaceuticals.

Doi:10.1021/jm00376a010
(1984)
Electroreductive Carbofunctionalization of Alkenes with Alkyl Bromides via a Radical-Polar Crossover Mechanism

Doi:10.1021/jacs.0c08532
(2020)
Doi:10.1002/ejoc.201701726
(2018)
Tannins of Coriaria japonica A. GRAY. I. Coriariins A and B, new dimeric and monomeric hydrolyzable tannins

Doi:10.1248/cpb.34.4092
(1986)
Synthesis of 1,2,3,4-tetrahydrocarbazoles and related tricyclic indoles

Doi:10.1016/j.tet.2006.11.052
(2007)

Article Doi