
Journal of Chemical and Engineering Data p. 481 - 483 (1982)
Update date:2022-07-29
Topics: Synthesis Catalyst Purification Structure-Activity Relationship (SAR) Reaction Monitoring Solvent Selection Amide Bond Formation Byproducts Spectroscopic Characterization Reaction yield Pharmacological screening Benzylation
Agwada, Vincent C.
Six N-benzylphenylacetamides variously substituted on the acyl part with chloro, methyl, or methoxyl groups, including five new ones, were synthesized by heating their corresponding N-benzylammonium salts in o-xylene.Their IR, NMR, and mass-spectral (MS) data are presented and compared with those of the N-benzylbenzamides and N-benzylacetamide, respectively.
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