Syntheses, Kinetics, and Mechanism of Formation of Polynuclear Hydroxo-Bridged Complexes of (trans-1,2-Diaminocyclohexane)platinum(II)

Article abstract of DOI:10.1021/ja00381a016

The synthesis and 195Pt chemical shifts of the hydroxo-bridged dimer and trimer, isolated from an aquated solution of bis(nitrato)(trans-1,2-diaminocyclohexane)platinum (I), at different pH are described.The chemical shifts of these three complexes are widely separated, and 195Pt NMR provides a convenient method for the investigation of dimer formation kinetics from I.Rate constants for the dimerization reaction calculated at different pD, temperature, and concentration agree well with the hypothesis that dimerization occurs with a rate-limiting bimolecular reaction of an intermediate hydroxo species formed by the loss of a proton from the parent complex.