Nitrogen bridgehead compounds. 18. New antiallergic 4H-pyrido[1,2-a]pyrimidin-4-ones

DOI: 10.1021/jm00352a008

Source and publish data:

Journal of Medicinal Chemistry p. 1140 - 1145 (1982)

Update date:2022-08-05

Topics:

Authors:

Hermecz Hermecz

Breining

Meszaros

Horvath Horvath

Vasvari-Debreczy

Dessy Dessy

DeVos DeVos

Rodriguez

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Article abstract of DOI:10.1021/jm00352a008

A new type of antiallergic agent, 9-hydrazono-6,7,8,9-tetrahydro-4H-pyridol[1,2-α]pyrimidin-4-ones, was synthesized and evaluated for inhibitory effects in the rat reagenic passive cutaneous anaphylaxis (PCA) screen. Several racemic 6-methyl derivatives w

Full text of DOI:10.1021/jm00352a008

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