A New Synthesis of 3-Amino-2-alkenoates. Novel Synthetic Route to Amino Sugars N-benzoyl-L-daunosamine and -L-acosamine

Article abstract of DOI:10.1246/bcsj.60.2127

Alkanoate esters are found to couple with various nitriles to give (Z)-3-amino-2-alkenoates in good yields with the aid of a magnesium amide prepared by the reaction of ethylmagnesium bromide and diisopropylamine.The C-C bond forming reaction was applied