Synthesis and biological activity of benzothiazolo- and benzoxazolo[3,2-a]quinolinium salts

DOI: 10.1021/jm00353a020

Source and publish data:

Journal of Medicinal Chemistry p. 1378 - 1381 (1982)

Update date:2022-08-02

Topics:

Authors:

Cox Cox

Jackson Jackson

Vargas Vargas

Baez Baez

Colon Colon

Gonzalez

de Leon de Leon

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Article abstract of DOI:10.1021/jm00353a020

The hitherto unknown 3-nitrobenzothiazolo- and 3-nitrobenzoxazolo[3,2-a]quinolinium salts were synthesized via the photochemically induced cyclization of the corresponding 2-(2-chloro-5-nitrostyryl)benzothiazole and 2-(2-chloro-5-nitrostyryl)benzoxazole. Results on their cytotoxic and antitumor activity are presented.

Full text of DOI:10.1021/jm00353a020

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