Chemical and Pharmaceutical Bulletin p. 2359 - 2385 (1985)
Update date:2022-08-02
Topics: Synthesis Congeners Potent Inhibitors Platelet aggregation
Tanaka
Okamura
Bannai
Hazato
Sugiura
Manabe
Kamimoto
Kurozumi
Novel 7-thiaprostaglandin E1 derivatives and congeners were synthesized by a stepwise three-component coupling process, which involves the introduction of α-side chains (thiols) and β-side chains (organocopper reagents) into (R)-4-tert-butyldim
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