Conformations of Saturated Six-Membered Ring Phosphorus Heterocycles. cis- and trans-2-Oxo- and 2-Thio-2-(dimethylamino)-5-tert-butyl-1,3,2λ5-oxazaphosphorinanes: Molecules Related to Cyclophosphamide

DOI: 10.1021/ja00387a039

Source and publish data:

Journal of the American Chemical Society p. 6385 - 6392 (1982)

Update date:2022-08-03

Topics:

Authors:

Bajwa, Gurdip S.

Chandrasekaran, Subramanian

Hargis, J. Howard

Sopchik, Alan E.

Blatter, Duane

Bentrude, Wesley G.

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Article abstract of DOI:10.1021/ja00387a039

Several 5-tert-butyl-2-(dimethylamino)-1,3,2-oxazaphosphorinanes have been prepared.Included are the NH (3 and 4) and NPh (5 and 6) oxides and sulfides.The individual diastereomers of 3-6 were separated and the cis and trans geometries determined for 4 an

Full text of DOI:10.1021/ja00387a039

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