Application of the intermolecular α-amido-alkylation reaction for the synthesis of tertiary amides and 1-substituted 2-acyltetrahydroisoquinolines. Synthesis of (±)-carnegine

Article abstract of DOI:10.1080/00397919508015425

Adducts 4 of Schiff bases and 3,4-dihydroisoquinolines with acyl chlorides react with Grignard reagents 5 in an intermolecular α-amidoalkylation reaction to the corresponding tertiary amides or 1-substituted 2-acyltetrahydroisoquinolines.

Full text of DOI:10.1080/00397919508015425

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Synthetic Communications: An
International Journal for Rapid
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Organic Chemistry
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Application of the
Intermolecular α-Amido-
alkylation Reaction for
the Synthesis of Tertiary
Amides and 1-Substituted 2-
Acyltetrahydroiso-Quinolines.
Synthesis of (±)-Carnegine
Atanas P. Venkov a & Stela M. Statkova-Abeghe a
a Department of Chemistry, University of Plovdiv,
Plovdiv, 4000, Bulgaria
Published online: 23 Sep 2006.
To cite this article: Atanas P. Venkov & Stela M. Statkova-Abeghe (1995) Application
of the Intermolecular α-Amido-alkylation Reaction for the Synthesis of Tertiary
Amides and 1-Substituted 2-Acyltetrahydroiso-Quinolines. Synthesis of (±)-Carnegine,
Synthetic Communications: An International Journal for Rapid Communication of
Synthetic Organic Chemistry, 25:12, 1817-1824, DOI: 10.1080/00397919508015425
To link to this article: http://dx.doi.org/10.1080/00397919508015425
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