HIGHLY STEREOCONTROLLED REDUCTION OF α'-ALKOXYENONES TO GIVE EITHER THE THREO OR ERYTHRO ALLYLIC 1,2-DIOL. ASSIGNMENT OF THE THREO CONFIGURATION TO THE C-15,C-16 DIOL OF PUMILIOTOXIN B.

Article abstract of DOI:10.1016/S0040-4039(00)87340-2

Model studies indicate that the allylic diol of pumiliotoxin B has the threo configuration, and that this functionality can be prepared with excellent stereocontrol by reduction of an α'-t-butyldiphenylsilyloxyenone.