Tetrahedron p. 3059 - 3065 (1982)
Update date:2022-09-26
Topics:
Babudri, F.
Nunno, L. Di
Florio, S.
Metallation of 4-methyl-3,4-dihydro-3-oxo-2H-1,4-benzothiazine with LDA and subsequent reaction with aldehydes leads to diastereomeric aldols 4 and 5.Acetylation followed by acetic acid elimination of the aldols provides a stereoselective and high yield route to 2-alkylidene-3,4-dihydro-3-oxo-2H-1,4-benzothiazines.
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Doi:10.1039/c39820000769
(1982)Doi:10.1021/acs.joc.7b02885
(2018)Doi:10.1016/S0022-1139(00)82284-8
(1982)Doi:10.1021/jacs.6b12896
(2017)Doi:10.1002/adsc.200303241
(2004)Doi:10.1002/hlca.200690072
(2006)
