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PENICILLIN-CEPHALOSPORIN CONVERSION IV. DIRECT SYNTHESIS OF 3'-THIOSUBSTITUTED CEPHALOSPORINS FROM THIAZOLE-AZETIDINONES

DOI: 10.1016/S0040-4039(00)87378-5

Source and publish data:

Tetrahedron Letters p. 2495 - 2498 (1982)

Update date:2022-08-05

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Authors:

Torii, SigeruTorii, Sigeru

Tanaka, HideoTanaka, Hideo

Sasaoka, MichioSasaoka, Michio

Saitoh, NorioSaitoh, Norio

Siroi, TakashiSiroi, Takashi

Nokami, JunzoNokami, Junzo

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Article abstract of DOI:10.1016/S0040-4039(00)87378-5

Direct transformation of thiazoline-azetidinones 2, derived from penicillin G and V, into 3'-thio-substituted cephalosporins 4 has been performed by ring opening of the thiazoline moiety with sulfenyl chlorides followed by ring closure with NH3 in dimethy

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Full text of DOI:10.1016/S0040-4039(00)87378-5

Products guided by the article

Product name:(R)-2-{(1R,5R)-3-[Bis-(benzothiazol-2-ylsulfanyl)-phenyl-methyl]-7-oxo-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl}-3-chloromethyl-but-3-enoic acid benzyl ester

Cas No:83242-44-8

83242-44-8

R&D Labs maybe for 83242-44-8

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