Journal of Medicinal Chemistry p. 218 - 222 (1983)
Update date:2022-08-03
Topics: Chemical Compounds Experimental Antiinflammatory Agents
Haviv, Fortuna
DeNet, Robert W.
Michaels, Raymond J.
Ratajczyk, James D.
Carter, George W.
Young, Patrick R.
2-<(Phenylthio)methyl>pyridine derivatives (1a-e) inhibited the dermal reverse passive Arthus reaction (RPAR) in the rat.In the same model, indomethacin was inactive, and hydrocortisone was active.Compounds 1a-d also significantly reduced exudate volume and white blood cell accumulation in the pleural RPAR.This pattern of activity was similar to that of hydrocortisone and different from that of indomethacin.
View MoreTianjin Crest Pharmaceutical R&D Co., Ltd. （Tianjin Yao Technology Development Co., Ltd.）(expird)
Contact:+86-22-66211386
Address:Building B5-405, No, 80 4th Avenue, TEDA, Tianjin, China P.R. 300457
jintan yufan Medicine Raw materials Co.,Ltd.(expird)
Contact:86-519-82808282
Address:6th,Jincheng Huangzhuang
Xuzhou Tianrun Chemical Co.,Ltd
website:http://www.tianrunchem.cn
Contact:86-516-83832636
Address:fuxing road
Huludao Tianqi Shengye Chemical Co.,Ltd.
Contact:0086 429 2075777
Address:Area B,Shipbuilding Industry Park,Beigang District,Huludao City,Liaoning prov.,China
website:http://www.greenutra.cn
Contact:0086-411-39553357
Address:No. 7-1-1802, Huizhi Garden,Ocean Square,Dalian, 116033, China
Doi:10.1016/j.tetlet.2009.02.224
(2009)Doi:10.1021/jo00150a006
(1983)Doi:10.1021/np049873n
(2004)Doi:10.1016/j.carres.2012.03.037
(2012)Doi:10.1246/cl.1987.2187
(1987)Doi:10.1021/acs.jmedchem.9b01192
(2019)
