Stereospezific Synthesis of α,β-Dehydroamino Acids from β-Hydroxy α-Amino Acid Derivatives

Article abstract of DOI:10.1021/jo00154a040

A series of protected β-hydroxy α-amino acids have been converted stereospecifically to their dehydro derivatives by treatment with (diethylamino)sulfur trifluoride and pyridine, threo isomers giving rise to the Z derivatives and erythro isomers to the E derivatives.