Angewandte Chemie - International Edition p. 6649 - 6652 (2004)
Update date:2022-08-03
Topics:
Dahmen, Claudia
Auernheimer, Joerg
Meyer, Axel
Enderle, Anja
Goodman, Simon L.
Kessler, Horst
Giving cells some stick: Osteoblast adhesion to titanium, a common material for implants, is stimulated by coating with an optimized and highly specific nonpeptidic ligand for the αvβ3 integrin (see picture). This new technology is advantageous to conventional coating by peptides or proteins in many practical aspects (selectivity and activity, stability against enzymatic degradation, sterilization, costs).
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Doi:10.1016/j.jorganchem.2004.09.022
(2005)Doi:10.1002/jhet.5570190533
(1982)Doi:10.1021/ja043979n
(2005)Doi:10.1016/j.bmcl.2006.11.066
(2007)Doi:10.1023/B:RUJO.0000045201.90930.ff
(2004)Doi:10.1016/j.tet.2009.06.027
(2009)
