Tetrahedron Letters p. 4365 - 4368 (1982)
Update date:2022-09-26
Topics:
Kume, Akiko
Sekine, Mitsuo
Hata, Tsujiaki
A phthaloyl group has been introduced into the N6-amino group of deoxyadenosine via silylation followed by acylation.The phthaloyl group resulted in remarkable retarding effects on depurination, while it could be removed under milder conditions than the benzoyl group.Thus, a tetradeoxy-adenylate has been successfully synthesized in high yield.
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(2005)
