SYNTHESIS WITH α-CYANOENAMINES. 2-DIETHYLAMINO-4-LITHIO-4-PHENYLTHIO-2-BUTENONITRILE AS A β-CARBOXYL VINYL ANION EQUIVALENT.

DOI: 10.1016/S0040-4039(00)88717-1

Source and publish data:

Tetrahedron Letters p. 4251 - 4254 (1982)

Update date:2022-07-30

Topics:

Authors:

Lombaert,Stephane de

Lesur, Brigitte

Ghosez, Leon

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Article abstract of DOI:10.1016/S0040-4039(00)88717-1

The lithio derivative of 2-diethylamino-4-phenylthio-2-butenonitrile is a practical equivalent of the unknown β-carboxyl-vinyl anion, as shown by its facile alkylation with alkyl halides, aldehydes and α-enones, followed by hydrolysis, oxidation and elimination.

Full text of DOI:10.1016/S0040-4039(00)88717-1

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