SYNTHESIS WITH α-CYANOENAMINES. 2-DIETHYLAMINO-4-LITHIO-4-PHENYLTHIO-2-BUTENONITRILE AS A β-CARBOXYL VINYL ANION EQUIVALENT.

DOI: 10.1016/S0040-4039(00)88717-1

Source and publish data:

Tetrahedron Letters p. 4251 - 4254 (1982)

Update date:2022-07-30

Topics:

Authors:

Lombaert,Stephane de

Lesur, Brigitte

Ghosez, Leon

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)88717-1

The lithio derivative of 2-diethylamino-4-phenylthio-2-butenonitrile is a practical equivalent of the unknown β-carboxyl-vinyl anion, as shown by its facile alkylation with alkyl halides, aldehydes and α-enones, followed by hydrolysis, oxidation and elimination.

Full text of DOI:10.1016/S0040-4039(00)88717-1

Products guided by the article

Product name:3-Phenylsulfanyl-hex-5-enoic acid

Cas No:84837-77-4

R&D Labs maybe for 84837-77-4

NEW FORTUNE INDUSTRIAL CO.,LTD.

website:http://newfortune.lookchem.com/

Contact:+86-25-8645-9456

Address:C4-105 GREEN ISLAND FLOWER TOWN
Jiangxi Lanqi Fine Chemical S&T Co., Ltd.

Contact:+86-21-64891143

Address:XinJiShan Industrial Area, Zhangshu City, JiangXi Province, China
Hangzhou jls Flame Retardants Chemical Co.,Ltd

Contact:+86-571-87250387/87250386

Address:MOGANSHAN RODA 1418# SHANGCHENG INDUSTRIAL PARK
Tengzhou Runlong Fragrance Co., Ltd.

website:http://www.tzrunlong.com/

Contact:--

Address:No. 78, Fushan Road, Biomedical Industrial Park, Dawu Town, Tengzhou, Shandong, 277514 China
Hangzhou Chemfar Ltd.

Contact:+86-571-87859231, 87859237, 87859239

Address:1606,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China, 310053

Relevant to this article

Total enzymatic synthesis of the cholecystokinin octapeptide (CCK-8)

Doi:10.1002/hlca.200890128
(2008)
Reactions of N-alkoxycycliminium salts, XIII: Reactions of substituted 2-chloro-N-methoxy-pyridinium salts with carbanions

Doi:10.1002/ardp.19833160113
(1983)
Studies on the reactivity of the four-membered base-stabilized iminoalane [(Me₃N)HAlNDipp]₂ with elemental iodine

Doi:10.1002/zaac.200400105
(2004)
Aminomethyl tetrahydronaphthalene biphenyl carboxamide MCH-R1 antagonists-Increasing selectivity over hERG

Doi:10.1016/j.bmcl.2006.10.053
(2007)
Direct, enantioselective α-alkylation of aldehydes using simple olefins

Doi:10.1038/NCHEM.2797
(2017)
Inhibition of LPS-stimulated ROS production by fluorinated and hydroxylated chalcones in RAW 264.7 macrophages with structure-activity relationship study

Doi:10.1016/j.bmcl.2017.01.061
(2017)

Article Doi