Tetrahedron Letters p. 3491 - 3492 (1993)
Update date:2022-08-04
Topics:
Cabri
Zarini
D'Anello
Marchi
Bedeschi
Franceschi
Short syntheses of ritipenem acoxyl 1a and ritipenem 1b are reported. The syntheses start from (R)-4-acetoxy-(S)-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]azetidin-2-o ne 3 and are based on the incorporation of two 2C unites obtained by manipulation of glicolyc acid 4.
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