A NEW SYNTHETIC APPROACH TO AMINOGLYCOSIDE ANTIBIOTICS BY USE OF OXIDATIVE DECARBOXYLATION AND REDUCTIVE DEACETOXYLATION AS KEY-REACTIONS

DOI: 10.1016/S0040-4039(00)85695-6

Source and publish data:

Tetrahedron Letters p. 4717 - 4720 (1982)

Update date:2022-08-05

Topics:

Authors:

Yoshikawa, Masayuki

Ikeda, Yoshiharu

Kayakiri, Hiroshi

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Article abstract of DOI:10.1016/S0040-4039(00)85695-6

By use of a decarboxylation reaction with lead tetraacetate and a deacetoxylation reaction with sodium borohydride as key-reactions, paromamine (12) and tri-N-benzyloxycarbonylparomamine (12a) were synthesized from D-glucosamine.

Full text of DOI:10.1016/S0040-4039(00)85695-6

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