Synthesis of Novel 3-Methylstatine Analogues. Assignment of Absolute Configuration

DOI: 10.1021/jo00159a017

Source and publish data:

Journal of Organic Chemistry p. 1876 - 1879 (1983)

Update date:2022-08-04

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Authors:

Kawai, Megumi

Boparai, Amrit S.

Bernatowicz, Michael S.

Rich, Daniel H.

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Article abstract of DOI:10.1021/jo00159a017

The synthesis and stereochemical assignments of two new analogues of statine are reported.Boc-L-leucine was reacted with methyllithium in dimethoxyethane to produce the corresponding methyl ketone in 45-75percent yield.Addition of ethyl lithioacetate at -

Full text of DOI:10.1021/jo00159a017

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