STREOSELECTIVE REDUCTION OF THE STEROIDAL 23-EN-22-ONE: A ROUTE TO THE SIDE CHAIN OF THE PLANT GROWTH PROMOTER BRASSINOLIDE.

Article abstract of DOI:10.1016/S0040-4039(00)98469-7

The side chain of brassinolide (1) was streoselectively synthesized, in which the 20(S)- and the 22(R)-configurations were introduced by the alkylation (S_N2) of the 20(R)-tosyloxy steroid 7 with the protected cyanohydrin 8 followed by the streo