Topically active carbonic anhydrase inhibitors. 3. Benzofuran- and indole-2-sulfonamides

Article abstract of DOI:10.1021/jm00164a045

Derivatives of benzofuran- and indole-2-sulfonamide were prepared for evaluation as topically active ocular hypotensive agents. These compounds were found to be excellent inhibitors of carbonic anhydrase and to lower intraocular pressure in a rabbit model