BIOTRANSFORMATION OF 6-GINGEROL AND 6-SHOGAOL BY ASPERGILLUS NIGER

Article abstract of DOI:10.1016/S0031-9422(00)90835-5

6-Gingerol and 6-shogaol, the pungent constituents of Zingiber officinalis were biotransformed by Aspergillus niger. 6-Gingerol was converted to the corresponding primary alcohol as major product although a keto group is present in the molecule whereas the double bond and keto group of 6-shogaol were reduced and the terminal methyl group was further oxidized to afford a ketoalcohol and a diol.All metabolites obtained from both substrates are tasteless.The structures of the metabolites have been established by spectral evidence.The metabolic pathways of both substrates will be discussed.