Biological effects of modified colchicines. 2. Evaluation of catecholic colchicines, colchifolines, colchicide, and novel N-acyl- and N-aroyldeacetylcolchicines

DOI: 10.1021/jm00364a006

Source and publish data:

Journal of Medicinal Chemistry p. 1365 - 1369 (1983)

Update date:2022-07-30

Topics:

Authors:

Brossi Brossi

Sharma Sharma

Atwell Atwell

Jacobson

Iorio Iorio

Molinari

Chignell

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00364a006

A series of natural and synthetic colchicine derivatives was examined for their potency in the lymphocytic leukemia P388 screen in mice, for their toxicity in mice, and for their binding to microtubule protein. The natural alkaloids cornigerine and colchi

Full text of DOI:10.1021/jm00364a006

Products guided by the article

Product name:N-retinoyldeacetylcolchicine

Cas No:86436-47-7

R&D Labs maybe for 86436-47-7

HUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.

Contact:+86-186-02659358

Address:1004, building 3, Wanke Jinsemaitianyuan, 498 Guitang Road, Yuhua District, Changsha City, Hunan Province, China
Shandong Hongxiang Zinc Co., Ltd

Contact:086-0311-66187879

Address:DaWang developing zone
PINGYUAN SIHUAN PHARMACEUTICAL CO., LTD

Contact:+86-531-55696072

Address:#2766,yinxiu Road, Economic Development Zone, Pingyuan Country, Shandong Province, China.
suzhou chukai pharmateach co,.ltd

Contact:86-512-88812511

Address:Building 3, Wujiang Scientific Innovation Park, 2358 Changan Rd, Wujiang 215200, Jiangsu Province, P. R. China
Guangzhou Swan Chemical Co., Ltd.

Contact:+86-20-31075659

Address:NO.301, Hong ba fang investment BLDG 1,Guan chong village,Shiqi town,Panyu district,Guangzhou

Relevant to this article

Determination of the absolute configuration and the first total synthesis of (-)- and (+)-linderol A

Doi:10.1016/j.tetasy.2004.06.017
(2004)
Domino: N-/C-or N-/N-/C-arylation of imidazoles to yield polyaryl imidazolium salts via atom-economical use of diaryliodonium salts

Doi:10.1039/c9cc05237b
(2019)
Direct Coupling between β-Functionalized Organolithium Compounds and Aryl and Vinyl Halides

Doi:10.1016/S0040-4039(00)60038-2
(1992)
Molecular interaction between naphthalene and 2,4-dinitrophenol in solid state

Doi:10.1080/15421400701693484
(2007)
Synthesis of Substituted Benzo[b]thiophenes via Sequential One-Pot, Copper-Catalyzed Intermolecular C-S Bond Formation and Palladium-Catalyzed Intramolecular Arene-Alkene Coupling of Bis(het)aryl/alkyl-1,3-monothiodiketones and o-Bromoiodoarenes

Doi:10.1021/acs.orglett.7b00273
(2017)
A total synthesis of plumericin, allamcin, and allamandin. 1. Basic strategy

Doi:10.1021/ja00276a043
(1986)

Article Doi