STEREOCHEMISTRY OF THE ASYMMETRIC 1,4-HYDRIDE REDUCTION OF N-SUBSTITUTED DERIVATIVES OF Δ9,10-OCTAHYDRO-4-QUINOLONE

Article abstract of DOI:10.1007/BF00516215

It is shown that the reaction of LiAlH4 with Δ^9,10-octahydro-4-quinolones that have chiral (S)-sec-butyl and (S)-α-benzylethyl substituents at the nitrogen atom proceeds as asymmetric 1,4-hydride reduction with the primary formation of trans is