Tetrahedron p. 1673 - 1680 (1983)
Update date:2022-07-30
Topics:
Giannini, D. D.
Kelts, L. W.
Dominh, T.
Stern, M. H.
A study of the 1H and 13C NMR spectra of adducts arising from the condensation of o-phthalaldehyde with an amide or a sulfonamide established the stereochemistry and differentiated between phthalan and isoindoline products for this reaction.The steric properties of the 2,6-dichlorobenzamide adduct appear to influence the vicinal H, OH coupling constant associated with the isoindoline ring.
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