Tetrahedron Letters p. 1031 - 1034 (1983)
Update date:2022-08-03
Topics:
Husson, Aline
Besselievre, Richard
Husson, Henri-Philippe
The selective acylation of primary amine functions of polyamines with acylating agents derived from unprotected mono or o-dihydroxy aromatic acids is described.The key step of the method is the transient protection of the phenol groups during the preparation of the hydroxy-1-piperidine active esters.This method is especially applicable to the preparation of the radiolabelled polyamine derivatives.
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Doi:10.1002/chem.201905734
(2019)Doi:10.1002/oms.1210180203
(1983)Doi:10.1021/ic0509985
(2005)Doi:10.1002/ejoc.200600389
(2006)Doi:10.1016/j.jorganchem.2005.05.028
(2005)Doi:10.1021/ja01266a059
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