Chemical and Pharmaceutical Bulletin p. 720 - 724 (1996)
Update date:2022-08-03
Topics: Biological activities Polyacetylenes Drug Development Potential Applications Marine Organisms
Kobayashi, Motomasa
Mahmud, Taifo
Tajima, Hisashi
Wang, Weiqi
Aoki, Shunji
Nakagawa, Shinsaku
Mayumi, Tadanori
Kitagawa, Isao
Adociacetylenes A (1), B (2), C (3), and D (4) were isolated as new polyacetylenes from an Okinawan marine sponge of Adocia sp. Their chemical structures have been elucidated on the bases of their chemical and physico-chemical properties. Adociacetylenes A (1), C (3), and D (4) exhibited inhibitory activity in the in vitro endothelial cell-neutrophil leukocyte adhesion assay.
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