Marine natural products. XXXVI. Biologically active polyacetylenes adociacetylenes A, B, C, and D, from an Okinawa Marine Sponge of Adocia sp.

DOI: 10.1248/cpb.44.720

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 720 - 724 (1996)

Update date:2022-08-03

Topics: Biological activities Polyacetylenes Drug Development Potential Applications Marine Organisms

Authors:

Kobayashi, Motomasa

Mahmud, Taifo

Tajima, Hisashi

Wang, Weiqi

Aoki, Shunji

Nakagawa, Shinsaku

Mayumi, Tadanori

Kitagawa, Isao

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Article abstract of DOI:10.1248/cpb.44.720

Adociacetylenes A (1), B (2), C (3), and D (4) were isolated as new polyacetylenes from an Okinawan marine sponge of Adocia sp. Their chemical structures have been elucidated on the bases of their chemical and physico-chemical properties. Adociacetylenes A (1), C (3), and D (4) exhibited inhibitory activity in the in vitro endothelial cell-neutrophil leukocyte adhesion assay.

Full text of DOI:10.1248/cpb.44.720

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