The chemistry of clavulanic acid: Some reactions of esters under neutral, acidic and basic conditions

DOI: 10.1016/S0040-4039(00)87979-4

Source and publish data:

Tetrahedron Letters p. 2693 - 2696 (1983)

Update date:2022-07-29

Topics: Ester Nucleophile Rearrangement Clavulanic acid Ring cleavage Thioether Neutral Conditions Acidic Conditions Basic Conditions

Authors:

Brown Brown

Howarth Howarth

Ponsford

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)87979-4

Investigations into the chemistry of benzyl clavulanate under a variety of reaction conditions has led to acid catalysed one-step conversion to ether and thioether derivatives. Generation of nitrogen-containing displacement products proceeds via the react

Full text of DOI:10.1016/S0040-4039(00)87979-4

Products guided by the article

Product name:(2R,5R)-7-Oxo-3-[2-phenylsulfanyl-eth-(Z)-ylidene]-4-oxa-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester

Cas No:86826-46-2

R&D Labs maybe for 86826-46-2

Dongtai Xinyuan Chemical Co., Ltd.

Contact:+86-21-56733000

Address:404F, 99Nong No.117 Zhongtan Rd. Shanghai
ChangZhou XiaQing Chemical Co., Ltd.

Contact:+86-519-88721665

Address:3# Hengluo Road, Henglin Town, Changzhou City, Jiangsu Province，China
SNC | GOOD FORTUNE

Contact:0086-22-2822 1962 / 2822 1963

Address:B-808, No. 1, North-South Street, Hexi District,
Yixing Zhenfen Medical Chemical Co.Ltd

Contact:86-510-87552708

Address:Fenshui ,Yixing city,Jiangsu
Changzhou BaoKang Pharmaceutical & Chemical Co., Ltd

Contact:(86) 519-88782201 88784080 88785278

Address:Henglin town, changzhou,Jiangsu

Relevant to this article

A new route to acridines: Pauson-Khand reaction on quinoline-bearing 1-En-7-ynes leading to novel tetrahydrocyclopenta[c]acridine-2,5-diones

Doi:10.1055/s-2005-870016
(2005)
A thieno-2H-chromene α-amino acid derivative: Synthesis and photochromic properties

Doi:10.1021/ol051378a
(2005)
Synthesis of some derivatives of C-(1-deoxy-1-N-substituted-d- glucopyranosyl)formic acid (D-gluco-hept-2-ulopyranosonic acid) as potential inhibitors of glycogen phosphorylase

Doi:10.1016/j.carres.2005.06.033
(2005)
Palladium-catalyzed oxidative cyclizations: Synthesis of dihydropyranones and furanones

Doi:10.1021/jo051274d
(2005)
Allylpalladium complexes with P-stereogenic monodentate phosphines. Application in the asymmetric hydrovinylation of styrene

Doi:10.1021/om050421v
(2005)
Preparation of 1,4-hydrobenzoquinones by the PCC/SiO₂-promoted double oxidation of 3-cyclohexene-1,2-diols

Doi:10.1039/b511067j
(2005)

Article Doi