Journal of Medicinal Chemistry p. 1625 - 1630 (1983)
Update date:2022-08-03
Topics:
Denny
Atwell
Baguley
The clinical antileukemic drug amsacrine and analogues are thought to exert their biological activity by binding tightly but reversibly to DNA, with the acridine chromophore intercalated and the anilino group making additional binding contact in the minor
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