Aerosol Direct Fluorination Syntheses: Alkyl Halides, Neopentyl Chloride and Bromide, Free Radicals vs. Carbocations

DOI: 10.1021/jo00173a035

Source and publish data:

Journal of Organic Chemistry p. 4953 - 4957 (1983)

Update date:2022-08-04

Topics:

Authors:

Adcock, James L.

Evans, William D.

Heller-Grossman, Lilly

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00173a035

Aerosol direct fluorination of neopentyl chloride produces perfluoroneopentyl chloride in 74percent yields.Analogous fluorination of neopentyl bromide produces perfluoroisopentane in 63percent yield.Data are presented that support a carbocation rearrangement in the fluorination of neopentyl bromide.The carbocations are presumed to arise from disproportionation of neopentylbromine fluorides.

Full text of DOI:10.1021/jo00173a035

Products guided by the article

Product name:Propane, 2-(chlorodifluoromethyl)-1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)-

Cas No:87136-72-9

R&D Labs maybe for 87136-72-9

Chengdu CSH Pharmaceutical Co.,ltd

Contact:+86-(28)-85321971

Address:Block B,New Hope Int. Tian Fu New District, Chengdu, Sichuan, China
Winchem Industrial Co. Ltd.(expird)

Contact:86-574-83851061 86-574-87083208

Address:Room 905, No.3 Building,East Business Center, 456 Xingning Road, Ningbo City,China
RongCheng Tianyu Technology Co.,Ltd.

Contact:86-631-7519595

Address:220Ping Donghai Road RongChengCity,ShangDong Province China
shanghai hekang chemical co.ltd

Contact:021-54173790

Address:328 WuHe Road, Building #A, 2nd Floor, Minhang, Shanghai 201109, China
Innua Petrochem Ltd.

Contact:+1-284-4950244

Address:Box 3069, Road Town, Tortola, British Virgin Islands

Relevant to this article

A new type of ketolides bearing an N-aryl-alkyl acetamide moiety at the C-9 iminoether synthesis and structure-activity relationships

Doi:10.1016/j.bmc.2005.07.041
(2005)
Modified biphenyl Hsp90 C-terminal inhibitors for the treatment of cancer

Doi:10.1016/j.bmcl.2017.07.030
(2017)
Palladium-Catalyzed Synthesis of Alkynes via a Tandem Decarboxylation/Elimination of (E)-Enol Triflates

Doi:10.1021/acs.orglett.6b01904
(2016)
Total synthesis of aspercyclide C

Doi:10.1039/b512877c
(2005)
A valuable synthesis of pyrrolo[1,2-a]quinoxalines, indolo[1,2-a] quinoxalines and their aza-analogues by palladium-catalyzed intramolecular carbon-nitrogen bond formation

Doi:10.1055/s-2005-916033
(2005)
Synthetic and theoretical investigation on the one-pot halogenation of β-amino alcohols and nucleophilic ring opening of aziridinium ions

Doi:10.1039/c5ob01692d
(2016)

Article Doi