Aerosol Direct Fluorination Syntheses: Alkyl Halides, Neopentyl Chloride and Bromide, Free Radicals vs. Carbocations

DOI: 10.1021/jo00173a035

Source and publish data:

Journal of Organic Chemistry p. 4953 - 4957 (1983)

Update date:2022-08-04

Topics:

Authors:

Adcock, James L.

Evans, William D.

Heller-Grossman, Lilly

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Article abstract of DOI:10.1021/jo00173a035

Aerosol direct fluorination of neopentyl chloride produces perfluoroneopentyl chloride in 74percent yields.Analogous fluorination of neopentyl bromide produces perfluoroisopentane in 63percent yield.Data are presented that support a carbocation rearrangement in the fluorination of neopentyl bromide.The carbocations are presumed to arise from disproportionation of neopentylbromine fluorides.

Full text of DOI:10.1021/jo00173a035

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