Tetrahedron p. 2255 - 2258 (1983)
Update date:2022-08-03
Topics:
Vargha, H. S.
Medzihradszky-Schweiger, H.
Ruff, F.
Medzihradszky, K.
Intramolecular cyclization of the N-(2-chloroethylcarbamoyl) derivatives of glycine, valine and phenylalanine give imidazolidone, oxazoline and hydantoin derivatives.The imidazolidone and oxazoline derivatives possess alkylating activity toward NBP, but the hydantoins do not.N-(2-Chloroethylcarbamoyl)glycine reacts with the mercapto group of cysteine; thus, this alkylating group may be useful for receptor labelling.
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Doi:10.1080/00397919508013857
(1995)Doi:10.1021/ja058514r
(2006)Doi:10.1021/acs.bioconjchem.8b00574
(2018)Doi:10.1002/ejoc.200500450
(2005)Doi:10.1055/s-1983-30379
(1983)Doi:10.1016/S0040-4039(00)88095-8
(1983)
