Journal of Organic Chemistry p. 4621 - 4628 (1983)
Update date:2022-08-03
Topics:
Marino, Joseph P.
Linderman, Russell J.
The reactivity of substituted (α-carbethoxyvinyl)cuprate reagents with various electrophiles has been studied systematically.The reaction of this type of cuprate reagent with ketones and epoxides leads to high yields of isomerically pure olefinic esters, while its condensation reaction with aldehydes produced mixtures of isomers.The stereochemistry of the condensation reaction with carbonyl compounds is explained by a steric control mechanism involving an allenoate intermediate.
View Morehangzhou verychem science and technology co.ltd
website:http://www.verypharm.com
Contact:+86-571-88162785; 88162786
Address:F1502, 753 Shenhua road, Hangzhou, China
RongCheng K&S Chemical Co.,Ltd
Contact:0631-7336369
Address:rongcheng ,shandong province china
Chemsky（shanghai）International Co.,Ltd.
Contact:0
Address:0
Contact:+86-18653358619
Address:zibo
Contact:0086 533 2282832
Address:Zibo，Shandong
Doi:10.1021/ol052542x
(2006)Doi:10.1021/jm501532z
(2014)Doi:10.1021/jo801659g
(2009)Doi:10.1016/j.cclet.2018.01.002
(2018)Doi:10.1021/jo00112a019
(1995)Doi:10.1016/j.tetlet.2011.03.007
(2011)
