Steroidal glycosides from the subterranean parts of Liriope spicata var. prolifera

Article abstract of DOI:10.1016/0031-9422(96)00228-2

In a continuation of phytochemical studies on the underground organs of Liriope spicata var. prolifera, four new steroidal glycosides, lirioproliosides A-D, along with two known compounds, 25(S)-ruscogenin 1- O[a-L-rhamnopyranosyl(1 → 2)]β-D-xylopyranosyl(1 → 3)-β-D-fucopyranoside and ophiopogonin A, were identified. The structures of lirioproliosides A-D were established by a combination of spectroscopic and chemical methods as 25(S)-ruscogenin 1-O-[α-L-rhamnopyranosyl(1 → 2)][β-D-xylopyranosyl(1 → 3)]-β-D-fucopyranoside-3-O-α-L-rhamnopyranoside, 25(S)-ruscogenin 1-O-[3- O-acetyl-α-L-rhamnopyranosyl(1 → 2)]-β-D-fucopyranoside, 25(S)-ruscogenin (1-O-[2-O-acetyl-α-L-rhamnopyranosyl(1 → 2)]-β-D-fucopyranoside and ruscogenin (1-O-[2-O-acetyl-α-L-rhamnopyranosyl(I → 2)]-β-D- fucopyranoside, respectively. Among these steroidal glycosides, ophiopogonm A and lirioprolioside B, and lirioproliosides C and D, were isolated as epimeric pairs.