Quinazolines and 1,4-Benzodiazepines. 90. Structure-Activity Relationship between Substituted 2-Amino-N-(2-benzoyl-4-chlorophenyl)acetamides and 1,4-Benzodiazepinones

DOI: 10.1021/jm00351a009

Source and publish data:

Journal of Medicinal Chemistry p. 1050 - 1055 (1982)

Update date:2022-07-29

Topics: Structure-Activity Relationship 1,4-Benzodiazepines Quinazolines

Authors:

Fryer, R. Ian

Leimgruber, Willy

Trybulski, Eugene J.

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Article abstract of DOI:10.1021/jm00351a009

The syntheses of 2-amino-N-(2-benzoyl-4-chlorophenyl)acetamides are reported.The pharmacological properties of these compounds were compared with data obtained from the corresponding cyclized products<5-(2,6-dichlorophenyl)-1,4-benzodiazepin-2-ones>.Evide

Full text of DOI:10.1021/jm00351a009

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