Journal of the American Chemical Society p. 7345 - 7352 (1983)
Update date:2022-08-05
Topics:
Ihara
Haga
Yonekura
et al.
A novel efficient beta -lactam synthesis was achieved by two successive processes (sulfeno-cycloamination), addition of phenysulfenyl chloride to alpha , beta -unsaturated amides followed by base treatment. Key synthetic intermediates of monobactams and nocardicin derivatives were obtained via this method. construction of the 1-carbapenam ring system by the sulfenocycloamination is also described.
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