1,4-DIANION OF ACETOPHENONE N-ETHOXYCARBONYLHYDRAZONE AS A SYNTHETIC INTERMEDIATE

Article abstract of DOI:10.1016/S0040-4039(00)88145-9

Various β-hydroxyketones and α,β-unsaturated ketones were prepared by the reaction of aldehydes and ketones with 1,4-dianion (2) which is derived from acetophenone N-ethoxycarbonylhydrazone (1) with butyllithium.In the reaction of 2 with carbonyl compounds such as ester, amide, acid anhydride, acyl chloride, and alkyl carbonate, pyrazole derivatives were obtained in good yields.