Bioorganic and Medicinal Chemistry Letters p. 1969 - 1975 (2012)
Update date:2022-08-04
Topics:
Hieke, Martina
R?dl, Carmen B.
Wisniewska, Joanna M.
La Buscató, Estel.
Stark, Holger
Schubert-Zsilavecz, Manfred
Steinhilber, Dieter
Hofmann, Bettina
Proschak, Ewgenij
A novel class of 5-lipoxygenase (5-LO) inhibitors characterized by a central imidazo[1,2-a]pyridine scaffold, a cyclohexyl moiety and an aromatic system, is presented. This scaffold was identified in a virtual screening study and exhibits promising inhibi
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