Cytochrome P-455 nm Complex Formation in the Metabolism of Phenylalkylamines. 8. Stereoselectivity in Metabolic Intermediary Complex Formation with a Series of Chiral 2-Substituted 1-Phenyl-2-aminoethanes

DOI: 10.1021/jm00369a018

Source and publish data:

Journal of Medicinal Chemistry p. 342 - 346 (1984)

Update date:2022-08-03

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Authors:

Paulsen-Soerman, Ulla B.

Joensson, Karl-Henrik

Lindeke, Bjoern G. A.

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Article abstract of DOI:10.1021/jm00369a018

The formation of cytochrome P-450 metabolic intermediary (MI) complexes from the enantiomers of four 2-alkyl-substituted 1-phenyl-2-aminoethanes was investigated during reduced nicotinamide adenine dinucleotide phosphate (NADPH) dependent metabolism in li

Full text of DOI:10.1021/jm00369a018

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